Anti-Glomerular Basement Membrane Test



Test Description

The Anti-Glomerular Basement Membrane Test (ANTI-GBM Test ) test is used to diagnose anti-GBM disease, a rare autoimmune disorder where the body’s immune system produces antibodies that attack the glomerular basement membrane in the kidneys and, in some cases, the lungs. This condition can lead to rapidly worsening kidney failure and lung disease. The test detects the presence of anti-GBM antibodies in the blood, which is crucial for an accurate diagnosis and to guide treatment.

Indications of the Test

The test is indicated for individuals who exhibit symptoms of anti-GBM disease, such as coughing up blood, dry cough, shortness of breath, and chest pain. It is also recommended for those at risk of the condition, including young, white men aged 15-35, as the disease most commonly affects this demographic.

Patient Preparation/Instructions

There are no specific patient preparations for this test. However, individuals should inform their healthcare provider about any medications or supplements they are taking, as these might affect the test results.

Typical Reference Values

The typical reference values for the anti-GBM test are the absence of anti-GBM antibodies in the blood. The presence of these antibodies indicates a positive result, which may suggest the presence of anti-GBM disease.

Turnaround Time

The turnaround time for the Anti-GBM test is usually a few days. However, this may vary depending on the laboratory and the specific testing methods used.

Order This Test

You can order the Anti-GBM test from anywhere in Kenya by clicking the “Order Test” button and adding it to your cart. Once the test is ordered, you can proceed to complete the purchase by checking out.


[1] Goodpasture’s Syndrome (Anti-GBM disease) – Penn Medicine
[2] Anti-GBM (Goodpasture’s) Disease – NIDDK
[3] Antiglomerular Basement Membrane Disease: Practice Essentials, Background, Pathophysiology
[4] Anti-GBM Antibody Disease: Practice Essentials, Pathophysiology, Etiology
[5] Anti-GBM Disease | UNC Kidney Center

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