The Malaria PCR Test is a highly sensitive molecular test used to detect and identify malaria-causing parasites in the blood. It works by amplifying parasite DNA, allowing for detection even when parasite levels are too low to be seen under a microscope. This makes it ideal for confirming malaria in difficult or unclear cases.Unlike rapid diagnostic tests (RDTs) or traditional microscopy, PCR can accurately identify all Plasmodium species, including:
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Plasmodium falciparum
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Plasmodium vivax
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Plasmodium ovale
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Plasmodium malariae
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Plasmodium knowlesi
It can also detect mixed infections and very low levels of parasites that other tests may miss.
Indications for Testing
The malaria PCR test may be recommended if:
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You have unexplained fever and recently traveled to a malaria-endemic area.
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Previous RDT or microscopy results were negative, but symptoms persist.
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Your doctor needs to confirm the species before treatment (especially for P. vivax or P. ovale).
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You’re undergoing clinical trial monitoring or advanced care for severe malaria.
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You’re part of public health surveillance or resistance tracking programs.
Patient Preparation / Instructions
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No fasting or special preparation is needed.
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Inform your doctor if you’ve taken any antimalarial drugs, had prior malaria, or recently traveled to endemic regions.
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A small amount of blood (1–2 mL) will be collected in a special EDTA tube.
You may feel slight discomfort or bruising at the site of the blood draw, but this is typically minor.
Interpreting Results
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Positive: Confirms malaria infection. The report specifies which Plasmodium species was detected.
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P. vivax or P. ovale: Requires additional treatment (primaquine) for dormant liver stages
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P. falciparum: Careful monitoring is essential due to potential severity or resistance
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Negative: Malaria is unlikely, especially if clinical suspicion is low.
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False negatives: Rare but possible if technical inhibitors are present
Comparison with Other Tests
| Test Type | Pros | Limitations |
|---|---|---|
| Microscopy | Standard method, shows parasite count | Misses low parasitemia, needs trained staff |
| RDT | Fast and easy to use | Less sensitive, cannot confirm species |
| PCR | Most sensitive, detects all species | More expensive, longer turnaround |
Turnaround Time
Results are typically ready within 10 to 14 days, depending on laboratory processing time and workload.
Order the Malaria PCR Test
Click the ‘Order Test’ button to add the Malaria PCR Test to your cart, or visit our lab in Kilimani, Nairobi to get started.
