Test Description
The Phospholipid Profile is a laboratory test designed to detect the presence of specific antibodies associated with Antiphospholipid Syndrome (APS).
This autoimmune disorder is characterized by recurrent thrombosis (blood clots) and/or pregnancy complications, such as miscarriages or pre-eclampsia.
The profile typically measures several types of antibodies, including:
- Lupus Anticoagulant (LA)
- Anticardiolipin Antibodies (aCL) IgG and IgM
- Anti-β2 Glycoprotein I Antibodies (anti-β2GPI) IgG and IgM
These antibodies are directed against membrane phospholipids and their associated proteins, which play a crucial role in blood coagulation.
Indications of the Phospholipid Profile Test
The Phospholipid Profile is indicated for patients who may have:
- Recurrent venous or arterial thrombosis.
- History of multiple miscarriages or pregnancy-related complications.
- Difficulty conceiving or experiencing adverse pregnancy outcomes.
- Symptoms suggestive of APS, especially in conjunction with other autoimmune disorders like systemic lupus erythematosus (SLE).
Patient Preparation/Instructions
Patients are generally advised to follow these instructions before the test:
- Fasting: Fasting is not usually required, but it’s best to confirm with your healthcare provider.
- Medications: Inform your doctor about any medications you are taking, as some may affect test results.
- Hydration: Drink plenty of water before the test to facilitate blood draw.
Typical Reference Values
Reference values can vary based on the laboratory but generally include:
- Lupus Anticoagulant: Negative
- Anticardiolipin Antibodies:
- IgG: < 20 GPL units
- IgM: < 20 MPL units
- Anti-β2 Glycoprotein I Antibodies:
- IgG: < 20 units
- IgM: < 20 units
Persistent positive results on two or more occasions at least 12 weeks apart are typically necessary for a diagnosis of APS.
Turnaround Time
The typical turnaround time for the phospholipid Profile results is approximately 5 working days, depending on the laboratory processing times.
Order This Test
To order the phospholipid Profile, please click the ‘Order Test’ button and add it to your cart. This will initiate the process for obtaining this important diagnostic test.
