The Albumin Level / Cerebrospinal Fluid (CSF) Test measures the amount of albumin in your spinal fluid. Albumin is a protein made by the liver and is normally found in very small amounts in the CSF. This test helps check the health of your blood-brain barrier (BBB) the protective layer that controls what enters the brain from the bloodstream. When the blood-brain barrier is damaged, albumin can leak into the CSF. High levels may be a sign of inflammation, infection, or other problems affecting the brain and spinal cord.
Indications for the Albumin / CSF Test
Your doctor shall recommend this test if you:
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Have symptoms of a nervous system condition such as multiple sclerosis (MS), Guillain-Barré syndrome, or meningitis
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Are being monitored for a neurodegenerative disease like ALS (amyotrophic lateral sclerosis)
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Need evaluation for unexplained neurological symptoms such as weakness, numbness, or confusion
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Show signs of a possible infection or inflammation in the brain or spinal cord
This test can also help doctors understand the severity and progression of diseases affecting the central nervous system.
Patient Preparation/Instructions
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No fasting is required, and there are no special dietary restrictions.
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Avoid heavy exercise before the test.
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Let your healthcare provider know about any medications, allergies, or bleeding problems.
How the Test is Done
The test involves a lumbar puncture (spinal tap), a procedure where a small sample of CSF is collected from the lower back using a thin needle. This is done under sterile conditions and usually takes just a few minutes.You’ll be asked to lie still while the sample is collected. The procedure may feel uncomfortable, but it is generally safe and well-tolerated.
When the test is done you are advised to
- Rest for a few hours
- Avoid heavy lifting, bending, or intense activity for 24 hours
- Drink plenty of fluids to help prevent headaches
Reference Values
Normal albumin levels in CSF depend on age, but for most adults, they fall within:
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10–45 mg/dL
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Levels above 50 mg/dL may suggest a problem with the blood-brain barrier
Interpretation of Results
To evaluate how well your blood-brain barrier is working, doctors may calculate the albumin index, which compares the amount of albumin in your spinal fluid to that in your blood:
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Less than 9: Normal
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9–14: Slight impairment
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15–30: Moderate impairment
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31–100: Severe impairment
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Over 100: Complete breakdown of the barrier
Sometimes, the test is done alongside other markers, such as IgG (an immune protein), to give more detailed insights.
Turnaround Time
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Results are usually ready within 3 to 5 days.
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In some cases, results may be faster if automated testing is available
Order Albumin level/CSF Test
To get started, click the ‘Order Test’ button and add the Albumin Level / CSF Test to your cart.
You’re also welcome to visit our Kilimani, Nairobi laboratory for more information or assistance.
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