FRAT Test (Folate Receptor Autoantibody Test)

FRAT Test:  What it tests

The FRAT test (Folate Receptor Autoantibody Test) is a blood test that detects whether your body has antibodies (autoantibodies) that target the folate receptor alpha (FRα).

This receptor is crucial for transporting folate (vitamin B9) to the brain and other vital tissues.

If these autoantibodies are present, they may block or interfere with folate transport, potentially leading to symptoms related to folate deficiency, especially in the brain—even when blood folate levels are normal.

Reason for Ordering FRAT Test

Doctors may recommend a FRAT test if you or your child experiences:

• Neurodevelopmental delays or autism spectrum disorder (ASD)

• Speech delays

• Unexplained seizures

• Developmental regression

• Behavioral or psychiatric concerns

• Suspected cerebral folate deficiency

• A history of pregnancy with neural tube defects or unexplained infertility

This test can also be considered for adults with unexplained neurological or psychiatric symptoms.

Patient Preparation/Instructions – Any preparations needed before the test

• No special fasting or preparation is required before the FRAT blood test.

• You can continue your usual medications unless your doctor advises otherwise.

• Inform your healthcare provider about any supplements or medicines you are taking.

Normal result ranges for FRAT Test

• Autoantibodies Not Detected: This is considered a normal result, indicating no interference with folate transport.

• Autoantibodies Detected: Levels may be reported as “negative”, “low”, “medium”, or “high.” Higher levels suggest a greater likelihood of problems with folate transport to the brain.

Reference ranges can vary between laboratories; your doctor will interpret your results based on these ranges and your individual situation.

Time it takes to get Report – How long results usually take

• Results are usually available within 1–4 weeks after your blood sample is collected, depending on laboratory processing times.

How to order the test – Step-by-step guide

1. Visit Labtestzote’s Website: Go to the Labtestzote online platform.

2. Find the FRAT Test: Search for “Folate Receptor Autoantibody Test” or “FRAT Test” in the test catalog.

3. Book Your Test: Select your preferred lab location in Nairobi or another available Kenyan site. Choose your appointment date and time.

4. Attend the Appointment: Visit the selected Labtestzote collection center for a simple blood draw.

5. Sample Analysis: Your sample will be sent for specialized processing.

6. Get Your Results: You will receive your test results securely online or be notified when they are ready for collection.

7. Discuss Results: Consult your healthcare provider to review your results and discuss next steps.

 

Related Tests

1. Folate level, Serum
2. Vitamin B12, Serum

Labtestzote proudly serves Nairobi and the whole of Kenya, ensuring accessible and reliable diagnostic testing