What is the Anti dsDNA Antibodies Test?
The Anti-dsDNA Antibodies Test is a blood test that measures the presence and amount of antibodies directed against double-stranded DNA (dsDNA) in your blood. These antibodies are a type of autoantibody, meaning they target your own body’s tissues, specifically the DNA found in cell nuclei. The test is highly specific for diagnosing systemic lupus erythematosus (SLE), an autoimmune disease, and is also used to monitor disease activity and flares.
Main reasons or symptoms for ordering the test
Doctors may recommend this test if you have symptoms or signs suggestive of lupus or other autoimmune diseases, such as:
-
Persistent joint pain or swelling
-
Unexplained skin rashes (especially a butterfly-shaped rash on the face)
-
Fatigue and weakness
-
Fever of unknown origin
-
Hair loss
-
Kidney problems (e.g., blood or protein in urine)
-
Sensitivity to sunlight
It is also used to monitor disease activity in people already diagnosed with lupus, especially if there are concerns about kidney involvement (lupus nephritis).
Patient Preparation/Instructions – Any preparations needed before the test
-
No special preparation is usually required.
-
Inform your doctor about any medications or supplements you are taking, especially biotin (vitamin B7), as it can interfere with the test. If you are taking biotin, you may be advised to stop it at least 72 hours before the test.
-
Stay well-hydrated before your blood draw.
Typical Reference Values – Normal result ranges (note they may vary)
Reference ranges can vary by laboratory, but typical values are:
| Result | IU/mL (International Units per millilitre) |
|---|---|
| Negative | < 5–10 IU/mL |
| Equivocal | 5–9 IU/mL |
| Positive | > 9–10 IU/mL |
Some labs may use slightly different cut-offs. Always interpret results with your doctor, considering your symptoms and other test results.
Time it takes to get Report – How long results usually take
-
Results are usually available within 24-48 hours
How to order the test
Step-by-step guide for ordering via Labtestzote (serving Nairobi and Kenya):
-
Visit the Labtestzote website and search for “Anti-dsDNA Antibodies Test” under the Autoimmune section.
-
Add the test to your cart and proceed to checkout.
-
Fill in your details and select your preferred sample collection location in Nairobi or other available locations in Kenya.
-
Make payment securely online.
-
Visit the selected laboratory at your scheduled time for a simple blood draw.
-
Receive your results via email or through your Labtestzote online account, usually within a few days.
Explore more:
