17-Hydroxy Progesterone Test (Dried Blood Spot sample)
The 17-Hydroxy Progesterone Test (Dried Blood Spot sample) is a laboratory analysis that measures the levels of 17-hydroxyprogesterone in dried blood samples. This hormone is primarily produced by the adrenal glands and is involved in the synthesis of cortisol and androgens. The 17-Hydroxy Progesterone Test (Dried Blood Spot sample) is particularly useful in diagnosing conditions related to adrenal gland function, including congenital adrenal hyperplasia (CAH).
Indications of the 17-Hydroxy Progesterone Test (Dried Blood Spot sample) Test
The 17-Hydroxy Progesterone Test (Dried Blood Spot sample) test is indicated for:
- Newborn Screening: To detect congenital adrenal hyperplasia in infants, especially those with ambiguous genitalia.
- Evaluation of Adrenal Disorders: To assess individuals showing symptoms of adrenal insufficiency or excess androgen production, such as:
- Excessive hair growth (hirsutism)
- Deepening of the voice
- Irregular menstruation or infertility
- Monitoring Treatment: To evaluate the effectiveness of treatment for adrenal disorders.
Patient Preparation/Instructions
- Medication Review: Patients should inform their healthcare provider about any medications they are taking, as certain drugs can affect hormone levels. It may be necessary to pause some medications prior to testing.
- Timing of Sample Collection: For women, it is often recommended to collect samples during specific phases of the menstrual cycle (early or mid-follicular phase) to ensure accurate results.
Typical Reference Values
Normal reference ranges for 17-OHP levels vary by age and sex:
- Newborns (>24 hours old): Less than 400 to 600 ng/dL (12.12 to 18.18 nmol/L)
- Children (pre-puberty): Approximately 100 ng/dL (3.03 nmol/L)
- Adults: Less than 200 ng/dL (6.06 nmol/L)
These values can vary slightly between laboratories, so it’s essential to discuss results with a healthcare provider.
Turnaround Time
The results for the 17-Hydroxy Progesterone test typically take a few days to process, depending on the laboratory’s workload and testing methods.
FAQs about the 17-Hydroxy Progesterone Test (dried blood spot sample)
What is the purpose of the 17-Hydroxy Progesterone Test (Dried Blood Spot sample) test?
- The 17-Hydroxy Progesterone Test (Dried Blood Spot sample) measures the levels of 17-hydroxyprogesterone in the blood. It is primarily used to diagnose and monitor conditions related to adrenal gland function, such as congenital adrenal hyperplasia (CAH).
Why is a dried blood spot sample used?
- Dried blood spot sampling is a convenient and minimally invasive method. It allows for easy collection, storage, and transportation of samples, especially in remote areas.
Who should take this 17-Hydroxy Progesterone Test (Dried Blood Spot Sample) Test?
- Newborns for screening congenital adrenal hyperplasia.
- Individuals with symptoms of adrenal disorders, such as excessive hair growth, irregular menstruation, or infertility.
- Patients are undergoing treatment for adrenal disorders to monitor progress.
How should I prepare for the test?
- Inform your healthcare provider about any medications you are taking, as some drugs can affect hormone levels. Women may need to schedule the test during specific phases of their menstrual cycle for accurate results.
What are the normal reference values?
- Newborns: Less than 400–600 ng/dL.
- Children (pre-puberty): Approximately 100 ng/dL.
- Adults: Less than 200 ng/dL. Reference ranges may vary slightly between laboratories.
How long does it take to get the results?
- Results are typically available within a few days, depending on the laboratory’s workload.
Are there any risks associated with the test?
- The test is safe, with minimal risks associated with the blood collection process, such as slight discomfort or bruising.
What do abnormal results mean?
- Elevated levels may indicate conditions like CAH or other adrenal disorders. Your healthcare provider will interpret the results in the context of your symptoms and medical history.
Why is a dried blood spot sample used?
- Dried blood spot sampling is a convenient and minimally invasive method. It allows for easy collection, storage, and transportation of samples, especially in remote areas.
How To Order 17-Hydroxy Progesterone Test (Dried Blood Spot sample)
Please click the ‘Order Test’ button and put the immunofluorescence analysis in Michel’s medium in your cart.
You are welcome to visit our laboratory in Kilimani, Nairobi.
This will initiate the process for obtaining your test
